SCHEMBL6936154

SCHEMBL6936154

CCOc1ccc(/C=C(/C)C(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.53
RAB9A P51151 2/20 0.53
TP53 P04637 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TSHR P16473 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
PARP10 Q53GL7 1/20 0.50
MAOB P27338 9/20 0.48
ABCG2 Q9UNQ0 1/20 0.46
ALDH1A1 P00352 1/20 0.44
PLK1 P53350 1/20 0.44
MAOA P21397 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6936156 1.00 NPC1 (0.53) NPC1RAB9ATP53SMN1; SMN2TSHR
SCHEMBL6935955 0.89 ABCG2 (0.48) NPC1RAB9ATP53SMN1; SMN2TSHR
SCHEMBL2457458 0.89 TSHR (0.50) NPC1RAB9ATP53TSHRABCG2
SCHEMBL2546691 0.89 ABCG2 (0.48) NPC1RAB9ATP53SMN1; SMN2TSHR
SCHEMBL2457460 0.89 TSHR (0.50) NPC1RAB9ATP53TSHRABCG2
SCHEMBL2483692 0.87 TSHR (0.51) NPC1RAB9ATP53TSHRABCG2
SCHEMBL2483695 0.87 TSHR (0.51) NPC1RAB9ATP53TSHRABCG2
SCHEMBL2451425 0.86 TP53 (0.53) NPC1RAB9ATP53TSHRALDH1A1
SCHEMBL2483740 0.86 TP53 (0.53) NPC1RAB9ATP53TSHRALDH1A1
SCHEMBL2451286 0.86 TP53 (0.53) NPC1RAB9ATP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170115491-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2017-04-27 US disclosed
EP-1372023-A2 Electro-optically concealable vehicle instrument panel and method of constructing the same Ergom Automotive S.p.a. (IT) 2003-12-17 EP disclosed