SCHEMBL6936408

SCHEMBL6936408

COCC(O)CNCCO

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
ADRB3 P13945 2/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ADRB2 P07550 3/20 0.34
ADRB1 P08588 2/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23587809 0.87 KDM4E (0.46) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL16582259 0.84 KDM4E (0.52) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL4845743 0.83 KDM4E (0.48) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL11237424 0.81 KDM4E (0.47) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL3753850 0.78 TSHR (0.42) KDM4EMAPTALDH1A1KMT2ATSHR
SCHEMBL13343920 0.78 KDM4E (0.44) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL9009590 0.77
Hydrochloric Acid SCHEMBL9668801 0.77 KDM4E (0.38) KDM4EKMT2AADRB3TSHRSMN1; SMN2
SCHEMBL29169706 0.76 ANPEP (0.45) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL29644203 0.76 KDM4E (0.38) KDM4EMAPTALDH1A1KMT2AADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805674-B1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORP (JP) 2003-03-12 EP claimed
US-6348200-B1 OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES KAO CORPORATION (JP) 2002-02-19 US claimed
EP-0805674-A1 SKIN AND HAIR COSMETIC COMPOSITIONS Kao Corporation (JP) 1997-11-12 EP claimed
WO-1997014401-A1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORPORATION (JP) 1997-04-24 WO claimed
JP-6321766-A None JP disclosed
EP-3385299-B1 AMINE POLYMER AND PREPARATION METHOD AND USE THEREOF. CHINA PETROLEUM & CHEM CORP (CN) 2020-11-04 EP disclosed
EP-2088150-A1 Fused pyrrolocarbazoles and methods for the preparation thereof Cephalon, Inc. (US) 2009-08-12 EP disclosed
EP-0805674-B1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORP (JP) 2003-03-12 EP disclosed
EP-0781780-B1 Polysaccharide derivative, and preparation process and use thereof KAO CORP (JP) 2002-05-29 EP disclosed
US-6348200-B1 OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES KAO CORPORATION (JP) 2002-02-19 US disclosed
EP-0691327-B1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME KAO CORP (JP) 1999-07-21 EP disclosed
US-5891450-A Polysaccharide derivative, and preparation process and use thereof KAO CORPORATION (JP) 1999-04-06 US disclosed
US-5723497-A AMINE ALCOHOL DERIVATIVES FOR WRINKLE RESISTNCE KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0781780-A2 Polysaccharide derivative, and preparation process and use thereof Kao Corporation (JP) 1997-07-02 EP disclosed
EP-0691327-A1 AMINE DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME Kao Corporation (JP) 1996-01-10 EP disclosed
JP-H06321766-A EXTERNAL APPLICATION FOR SKIN KAO CORP 1994-11-22 JP disclosed