SCHEMBL11237424

SCHEMBL11237424

COCC(O)CNCCN

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 1/20 0.47
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
ANPEP P15144 1/20 0.38
ADRB2 P07550 6/20 0.37
ADRB3 P13945 2/20 0.36
ADRB1 P08588 1/20 0.36
MEN1 O00255 1/20 0.36
CA12 O43570 1/20 0.36
CA6 P23280 1/20 0.36
CA7 P43166 1/20 0.36
RECQL P46063 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13343920 0.96 KDM4E (0.44) KDM4EKMT2AALDH1A1POLBMAPT
SCHEMBL13600228 0.83 KDM4E (0.44) KDM4EKMT2AALDH1A1POLBMAPT
SCHEMBL11231807 0.82 KDM4E (0.52) KDM4EKMT2AALDH1A1MAPTANPEP
SCHEMBL13343921 0.82 KDM4E (0.38) KDM4EKMT2AALDH1A1POLBMAPT
SCHEMBL16582259 0.82 KDM4E (0.52) KDM4EKMT2AALDH1A1POLBMAPT
SCHEMBL4845743 0.81 KDM4E (0.48) KDM4EKMT2AALDH1A1POLBMAPT
SCHEMBL6936408 0.81 KDM4E (0.43) KDM4EKMT2AALDH1A1POLBMAPT
SCHEMBL11231657 0.80 ALDH1A1 (0.41) KDM4EKMT2AALDH1A1ANPEPADRB2
SCHEMBL12794818 0.80 KDM4E (0.44) KDM4EKMT2AALDH1A1ANPEPADRB2
SCHEMBL11235646 0.80 KDM4E (0.53) KDM4EKMT2AALDH1A1ANPEPADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11872301-B2 Wetting composition including silicone polymer softening agent and wet wipes including the same KIMBERLY CLARK CO (US) 2024-01-16 US disclosed
US-7723335-B2 Triazine compounds and their use in forming multidimensional libraries for affinity chromatography PROMETIC BIOSCIENCES LTD. (IM) 2010-05-25 US disclosed
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11872301-B2 Wetting composition including silicone polymer softening agent and wet wipes including the same H1-2, H1-0, H1-4 KDM4E 870/4885KMT2A 126/4885ALDH1A1 1709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.