Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.44 |
| ▸ | PPARA | Q07869 | 12/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936549 | 1.00 | PPARG (0.44) | PPARGPPARAPPARDS1PR1RAB9A | |
| SCHEMBL6937657 | 0.92 | PPARG (0.44) | PPARGPPARAPPARDS1PR1 | |
| SCHEMBL6937655 | 0.92 | PPARG (0.44) | PPARGPPARAPPARDS1PR1 | |
| Hydrochloric Acid SCHEMBL6934331 | 0.91 | PPARG (0.46) | PPARGPPARAPPARDS1PR1 | |
| Hydrochloric Acid SCHEMBL6934326 | 0.91 | PPARG (0.46) | PPARGPPARAPPARDS1PR1 | |
| SCHEMBL27512142 | 0.86 | PPARG (0.39) | PPARGPPARAPPARDS1PR1 | |
| SCHEMBL6716302 | 0.82 | NPC1 (0.47) | PPARGPPARARAB9ANPC1GAA | |
| SCHEMBL6939062 | 0.81 | S1PR1 (0.44) | PPARGPPARAPPARDS1PR1RAB9A | |
| SCHEMBL6939060 | 0.81 | S1PR1 (0.44) | PPARGPPARAPPARDS1PR1RAB9A | |
| SCHEMBL6938739 | 0.80 | PPARG (0.47) | PPARGPPARAPPARDS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |