Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.44 |
| ▸ | PPARA | Q07869 | 13/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937657 | 1.00 | PPARG (0.44) | PPARGPPARAPPARDS1PR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6934331 | 0.99 | PPARG (0.46) | PPARGPPARAPPARDS1PR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6934326 | 0.99 | PPARG (0.46) | PPARGPPARAPPARDS1PR1ALDH1A1 | |
| SCHEMBL6936545 | 0.92 | PPARG (0.44) | PPARGPPARAPPARDS1PR1 | |
| SCHEMBL6936549 | 0.92 | PPARG (0.44) | PPARGPPARAPPARDS1PR1 | |
| SCHEMBL6715159 | 0.81 | NPC1 (0.48) | PPARGPPARAPPARDMAPT | |
| SCHEMBL6934345 | 0.81 | PPARA (0.64) | PPARGPPARAPPARD | |
| SCHEMBL6934350 | 0.81 | PPARA (0.64) | PPARGPPARAPPARD | |
| SCHEMBL6934075 | 0.80 | PPARG (0.46) | PPARGPPARAPPARDMAPT | |
| SCHEMBL6934076 | 0.80 | PPARG (0.46) | PPARGPPARAPPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | claimed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | claimed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | claimed |
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |