Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936506 | 0.90 | MAPT (0.44) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL6937958 | 0.87 | MAPT (0.44) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL5416313 | 0.83 | MAPT (0.71) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL5416306 | 0.83 | MAPT (0.71) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL6937483 | 0.83 | MAPT (0.45) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL7604277 | 0.81 | MAPT (0.43) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL8793307 | 0.81 | MAPT (0.50) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL6993715 | 0.76 | GRIA2 (0.47) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL5424614 | 0.76 | MAPT (0.62) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL5424606 | 0.76 | MAPT (0.62) | MAPTLMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802195-B1 | Substituted 2,3-benzodiazepine derivatives, process and intermediates for their preparation and pharmaceutical compositions comprising them as well as their use | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-11-19 | — | — | EP | disclosed |
| US-5807851-A | MUSCLE RELAXANTS; NERVOUS SYSTEM DISORDERS | EGIS GYOGYSZERGYAR RT. (HU) | 1998-09-15 | — | — | US | disclosed |
| EP-0802195-A2 | Substituted 2,3-benzodiazepine derivatives, process and intermediates for their preparation and pharmaceutical compositions comprising them as well as their use | EGIS GYOGYSZERGYAR RT. (HU) | 1997-10-22 | — | — | EP | disclosed |