Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936831 | 1.00 | STAT3 (0.41) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL1120039 | 0.89 | STAT3 (0.43) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL3979818 | 0.89 | STAT3 (0.43) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL1660141 | 0.89 | STAT3 (0.43) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL5569851 | 0.85 | STAT3 (0.43) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL13918179 | 0.85 | STAT3 (0.39) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL6323071 | 0.83 | CA9 (0.43) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL17233364 | 0.83 | CA9 (0.43) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL21239935 | 0.83 | ALDH1A1 (0.41) | STAT3CA1CA9CA12ALDH1A1 | |
| SCHEMBL1681609 | 0.83 | ALDH1A1 (0.41) | STAT3CA1CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |