Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.60 |
| ▸ | PPARD | Q03181 | 8/20 | 0.60 |
| ▸ | PPARA | Q07869 | 8/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939647 | 0.92 | PPARG (0.62) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6938580 | 0.91 | PPARG (0.57) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6938970 | 0.89 | PPARG (0.75) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6933003 | 0.87 | PPARD (0.80) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6933007 | 0.87 | PPARD (0.80) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6937003 | 0.86 | PPARG (0.60) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6938100 | 0.84 | PPARG (0.69) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6937010 | 0.84 | PPARG (0.68) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6932943 | 0.83 | PPARG (0.60) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6936461 | 0.83 | PPARG (0.59) | PPARGPPARDPPARACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |