Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532838 | 0.88 | SLC9A1 (0.68) | SLC9A1 | |
| SCHEMBL8571432 | 0.88 | SLC9A1 (0.63) | SLC9A1 | |
| Rimeporide SCHEMBL1019633 | 0.88 | SLC9A1 (1.00) | SLC9A1 | |
| Rimeporide SCHEMBL30309010 | 0.88 | SLC9A1 (1.00) | SLC9A1 | |
| Rimeporide SCHEMBL1022632 | 0.86 | SLC9A1 (0.97) | SLC9A1 | |
| Rimeporide SCHEMBL16712399 | 0.86 | SLC9A1 (0.97) | SLC9A1 | |
| SCHEMBL8531009 | 0.86 | SLC9A1 (0.85) | SLC9A1 | |
| Rimeporide SCHEMBL29406681 | 0.86 | SLC9A1 (0.97) | SLC9A1 | |
| SCHEMBL8575426 | 0.85 | SLC9A1 (0.60) | SLC9A1 | |
| SCHEMBL8441506 | 0.85 | SLC9A1 (0.82) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688331-B1 | NEW SULFATED LYSO-GANGLIOSIDE DERIVATIVES | FIDIA SPA (IT) | 2001-06-13 | — | — | EP | claimed |
| EP-0704431-B1 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GMBH (DE) | 2000-05-24 | — | — | EP | claimed |
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | claimed |
| EP-0704431-A2 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GmbH (DE) | 1996-04-03 | — | — | EP | claimed |
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-0725062-B1 | 4-mercapto-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2001-06-13 | — | — | EP | disclosed |
| EP-0723963-B1 | 4-amino-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2001-06-13 | — | — | EP | disclosed |
| EP-0704431-B1 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GMBH (DE) | 2000-05-24 | — | — | EP | disclosed |
| EP-0708088-B1 | Alkyl-5-methylsulphonyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 1999-03-24 | — | — | EP | disclosed |
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5700839-A | ANTIARRYTHMIA AGENTS; ACT AS INHIBITORS OF THE CELLULAR NA+/H+ ANTIPORTER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-23 | — | — | US | disclosed |
| US-5696167-A | 4-mercaptobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |
| EP-0725062-A1 | 4-mercapto-benzoylguanidine derivatives | MERCK PATENT GmbH (DE) | 1996-08-07 | — | — | EP | disclosed |
| EP-0723963-A1 | 4-amino-benzoylguanidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-31 | — | — | EP | disclosed |
| EP-0708088-A1 | Alkyl-5-methylsulphonyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0704431-A2 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |