Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723428 | 0.89 | CHRM2 (0.56) | CHRM2CHRM1MRGPRX4POLBMAPT | |
| SCHEMBL1783715 | 0.89 | CHRM2 (0.56) | CHRM2CHRM1MRGPRX4POLBMAPT | |
| Hydrochloric Acid SCHEMBL597394 | 0.88 | CHRM2 (0.55) | CHRM2CHRM1MRGPRX4POLBMAPT | |
| Hydrochloric Acid SCHEMBL597393 | 0.88 | CHRM2 (0.55) | CHRM2CHRM1MRGPRX4POLBMAPT | |
| SCHEMBL6934653 | 0.84 | CCR5 (0.46) | CHRM2CHRM1ALDH1A1 | |
| SCHEMBL27556305 | 0.84 | CHRM2 (0.48) | CHRM2CHRM1MRGPRX4POLBMAPT | |
| SCHEMBL27773494 | 0.84 | CHRM2 (0.48) | CHRM2CHRM1MRGPRX4POLBMAPT | |
| SCHEMBL6934786 | 0.84 | BCHE (0.43) | CHRM2CHRM1MAPTALDH1A1 | |
| SCHEMBL5179164 | 0.81 | CHRM2 (0.55) | CHRM2CHRM1MRGPRX4POLBMAPT | |
| SCHEMBL5179157 | 0.81 | CHRM2 (0.55) | CHRM2CHRM1MRGPRX4POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482635-C | Noval compounds, their use and preparation | PFIZER HEALTH AB (SE) | 2009-04-29 | — | — | CN | disclosed |
| CN-1636967-A | Noval compounds, their use and preparation | PFIZER (SE) | 2005-07-13 | — | — | CN | disclosed |
| EP-1019358-B1 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| CN-1251569-A | Novel compounds, their use and process for their preparation | PHARMACIA & UPJOHN AB (SE) | 2000-04-26 | — | — | CN | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |