Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499539 | 1.00 | CYP3A4 (0.65) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL581831 | 0.81 | CYP3A4 (0.55) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL31506484 | 0.81 | CYP3A4 (0.55) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL6182858 | 0.81 | MAPK1 (0.55) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL6349819 | 0.79 | CYP3A4 (0.52) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL136940 | 0.79 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL6754088 | 0.79 | CYP3A4 (0.68) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL30528041 | 0.77 | CYP3A4 (0.65) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL70542 | 0.77 | CYP3A4 (0.65) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL11876110 | 0.77 | CYP3A4 (0.94) | CYP3A4MAPK1TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595767-A | 1,4-benzodioxine and 1,4-benzodioxine derivatives and production thereof | SHIONOGI & CO., LTD. (JP) | 1986-06-17 | — | — | US | claimed |
| EP-0182302-A2 | Novel 1,4-benzodioxane and 1,4-benzodioxine derivatives and production thereof | SHIONOGI & CO., LTD. (JP) | 1986-05-28 | — | — | EP | claimed |
| JP-61118380-A | — | — | None | — | — | JP | disclosed |
| CN-110049864-A | Treatment of conversion coated metal substrates with preformed reaction products of catechol compounds and functionalized co-reactive compounds | 汉高股份有限及两合公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-106085907-B | The bacillus cereus of efficient degradation tetrachloro guaiacol and its application | 盐城工学院 | 2019-02-01 | — | — | CN | disclosed |
| CN-106085907-A | The bacillus cereus of efficient degradation tetrachloro guaiacol and application thereof | 盐城工学院 | 2016-11-09 | — | — | CN | disclosed |
| EP-1768970-B1 | SULFAMATE AND SULFAMIDE DERIVATIVES FOR THE TREATMENT OF EPILEPSY AND RELATED DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-09 | — | — | EP | disclosed |
| CN-103197062-B | A kind of method and special ELISA reagent kit thereof detecting dioxin | Hebei Yi Laisha Bioisystech Co., Ltd (CN) | 2015-12-23 | — | — | CN | disclosed |
| US-8937096-B2 | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder | JANSSEN PHARMACEUTICA NV (BE) | 2015-01-20 | — | — | US | disclosed |
| US-8853263-B2 | Co-therapy for the treatment of epilepsy and related disorders | JANSSEN PHARMACEUTICA NV (BE) | 2014-10-07 | — | — | US | disclosed |
| EP-1968572-B1 | USE OF BENZO-FUSED HETEROCYCLE SULFAMIDE DERIVATIVES FOR THE TREATMENT OF SUBSTANCE ABUSE AND ADDICTION | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-06 | — | — | EP | disclosed |
| EP-0188394-A1 | Process for purifying an aqueous solution of rare-earth salt by liquid-liquid extraction | RHONE-POULENC CHIMIE (FR) | 1986-07-23 | — | — | EP | disclosed |
| US-4595767-A | 1,4-benzodioxine and 1,4-benzodioxine derivatives and production thereof | SHIONOGI & CO., LTD. (JP) | 1986-06-17 | — | — | US | disclosed |
| JP-S61118380-A | NOVEL 1,4-BENZODIOXANE AND 1,4-BENZODIOXINE DERIVATIVE AND PREPARATION THEREOF | SHIONOGI & CO LTD | 1986-06-05 | — | — | JP | disclosed |
| EP-0182302-A2 | Novel 1,4-benzodioxane and 1,4-benzodioxine derivatives and production thereof | SHIONOGI & CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |
| EP-0076221-B1 | PROCESS FOR THE ETHERIFICATION OF PHENOLS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-02 | — | — | EP | disclosed |
| EP-0037353-B1 | PROCESS FOR THE ETHERIFICATION OF PHENOLS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-06-08 | — | — | EP | disclosed |
| EP-0046719-A1 | Process for the etherification of phenols | RHONE-POULENC INDUSTRIES (FR) | 1982-03-03 | — | — | EP | disclosed |
| EP-0037353-A1 | Process for the etherification of phenols | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-10-07 | — | — | EP | disclosed |
| US-3988318-A | HYDROXY-PHENOLS; PLASTICIZERS | GAF CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |