SCHEMBL70542

SCHEMBL70542

Oc1ccc(Cl)c(O)c1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.65
MAPK1 P28482 2/20 0.65
TSHR P16473 7/20 0.48
HSD17B10 Q99714 7/20 0.43
HPGD P15428 4/20 0.43
DPP4 P27487 1/20 0.42
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
CASP1 P29466 1/20 0.41
HSP90AA1 P07900 2/20 0.40
KDM4E B2RXH2 1/20 0.40
BRD4 O60885 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
PIM1 P11309 1/20 0.38
ESR1 P03372 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30528041 1.00 CYP3A4 (0.65) CYP3A4MAPK1TSHRHSD17B10HPGD
Phenol SCHEMBL29131413 0.86 MAPK1 (0.50) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL581831 0.81 CYP3A4 (0.55) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL31506484 0.81 CYP3A4 (0.55) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL6182858 0.81 MAPK1 (0.55) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL1477549 0.79 CYP3A4 (0.54) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL6349819 0.79 CYP3A4 (0.52) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL136940 0.79 CYP3A4 (1.00) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL7743436 0.77 CYP3A4 (0.75) CYP3A4MAPK1TSHRHSD17B10HPGD
SCHEMBL31392414 0.77 CYP3A4 (0.75) CYP3A4MAPK1TSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117233299-A Method for detecting halogenated polyphenol in drinking water by solid phase extraction-vacuum centrifugal concentration-liquid chromatography tandem mass spectrometry 浙江大学 2023-12-15 CN claimed
CN-116589475-B Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein 北京欧凯纳斯生化科技有限公司 2023-09-29 CN claimed
CN-116589475-A Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein 北京欧凯纳斯生化科技有限公司 2023-08-15 CN claimed
CN-111960932-B Dichlororesorcinol compound and preparation method and medical application thereof 沈阳药科大学 2022-11-08 CN claimed
CN-111960932-A Dichlororesorcinol compound and preparation method and medical application thereof 沈阳药科大学 2020-11-20 CN claimed
CN-103736239-A Fire extinguishing composition containing aldoketones compound XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-04-23 CN claimed
CN-103736237-A Fire extinguishing composition containing hydroxyketone compound and derivatives of hydroxyketone compound XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-04-23 CN claimed
WO-2007089785-A2 APPARATUS AND SEMICONDUCTOR CO-CRYSTAL UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2007-08-09 WO claimed
EP-1161414-B1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2003-10-01 EP claimed
US-20020055648-A1 Cyanate esters having flame resistant properties JPMORGAN CHASE BANK, N.A. 2002-05-09 US claimed
EP-1161414-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES Vantico AG (CH) 2001-12-12 EP claimed
US-6242638-B1 FIREPROOFING USING CURED MIXTURES VANTICO INC. 2001-06-05 US claimed
WO-2000055123-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2000-09-21 WO claimed
US-12023393-B2 Polymerizable 4,4′-spirobi[chromane]-2,2′-diones and curable compositions including the same SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-02 US disclosed
US-20240167922-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD KYOTO UNIVERSITY (JP) 2024-05-23 US disclosed
US-20240122815-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-04-18 US disclosed
EP-0037353-B1 PROCESS FOR THE ETHERIFICATION OF PHENOLS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-06-08 EP disclosed
EP-0076221-A1 Process for the etherification of phenols RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-04-06 EP disclosed
EP-0046719-A1 Process for the etherification of phenols RHONE-POULENC INDUSTRIES (FR) 1982-03-03 EP disclosed
EP-0037353-A1 Process for the etherification of phenols RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055648-A1 Cyanate esters having flame resistant properties PCCA, FABP4, MCCC2 CYP3A4 464/4885MAPK1 4514/4885TSHR 4633/4885
US-20240167922-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD TST, TTR, ALB CYP3A4 1594/4885MAPK1 1927/4885TSHR 2764/4885
US-12023393-B2 Polymerizable 4,4′-spirobi[chromane]-2,2′-diones and curable compositions including the same CTRB2, CBR1, CCNB3 CYP3A4 2233/4885MAPK1 2138/4885TSHR 1286/4885
US-20240122815-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME CTRB2, CBR1, CCNB3 CYP3A4 2210/4885MAPK1 2016/4885TSHR 1304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.