Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456235 | 1.00 | MAPT (0.59) | MAPTADRB2ADRB1ADRB3MAOB | |
| SCHEMBL9484001 | 0.93 | MAPT (0.59) | MAPTADRB2ADRB1ADRB3MAOB | |
| SCHEMBL9639807 | 0.93 | MAOB (0.56) | MAPTADRB2ADRB1ADRB3MAOB | |
| SCHEMBL9450093 | 0.89 | MAPT (0.58) | MAPTADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9511873 | 0.86 | MAPT (0.54) | MAPTADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9710281 | 0.86 | MAPT (0.53) | MAPTADRB2ADRB1ADRB3MAOB | |
| SCHEMBL4953172 | 0.83 | MAPT (0.66) | MAPTADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9456360 | 0.83 | MAPT (0.66) | MAPTADRB2ADRB1ADRB3LMNA | |
| SCHEMBL8537137 | 0.83 | KMT2A (0.52) | MAPTADRB2ADRB1ADRB3MAOB | |
| SCHEMBL8537143 | 0.83 | KMT2A (0.52) | MAPTADRB2ADRB1ADRB3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962445-B1 | Acetylene compound, liquid crystal composition and liquid crystal element | MITSUI CHEMICALS INC (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-6217793-B1 | Acetylene compound, liquid crystal composition and liquid crystal element | MITSUI CHEMICALS, INC. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0962445-A1 | Acetylene compound, liquid crystal composition and liquid crystal element | Mitsui Chemicals, Inc. (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5229032-A | Reacting p-aminobenzoic acid with sodium nitrite, then with alkylmercaptane, mineral acids to form alkylthiobenzoic acid, esterification | SHOWA DENKO K.K. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5055225-A | High speed response | SHOWA DENKO K.K. (JP) | 1991-10-08 | — | — | US | disclosed |