Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657813 | 0.89 | ADRB2 (0.52) | MAPTADRB2ADRB1ADRB3NPC1 | |
| SCHEMBL6658052 | 0.89 | ADRB2 (0.54) | MAPTADRB2ADRB1ADRB3NPC1 | |
| SCHEMBL6937628 | 0.86 | MAPT (0.59) | MAPTADRB2ADRB1ADRB3GAA | |
| SCHEMBL9484001 | 0.86 | MAPT (0.59) | MAPTADRB2ADRB1ADRB3GAA | |
| SCHEMBL9456235 | 0.86 | MAPT (0.59) | MAPTADRB2ADRB1ADRB3GAA | |
| SCHEMBL3235219 | 0.84 | ALOX5 (0.61) | MAPTNPC1GAAXBP1RAB9A | |
| SCHEMBL9228017 | 0.83 | MAPT (0.50) | MAPTNPC1SMN1; SMN2MAOBLMNA | |
| SCHEMBL6649144 | 0.82 | NPC1 (0.50) | MAPTADRB2ADRB1ADRB3NPC1 | |
| SCHEMBL9224554 | 0.82 | MAPT (0.49) | MAPTNPC1SMN1; SMN2LMNA | |
| SCHEMBL9223277 | 0.82 | MAPT (0.49) | MAPTNPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518636-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |