SCHEMBL6937649

SCHEMBL6937649

CC(OC(=O)C=CC(=O)OC(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937646 1.00 HCAR2 (0.38) HCAR2THRB
SCHEMBL7543886 0.98 HCAR2 (0.39) HCAR2THRB
SCHEMBL7543884 0.98 HCAR2 (0.39) HCAR2THRB
SCHEMBL7539857 0.95 HCAR2 (0.47) HCAR2THRB
SCHEMBL7539854 0.95 HCAR2 (0.47) HCAR2THRB
SCHEMBL9414023 0.93 HCAR2 (0.50) HCAR2THRB
SCHEMBL8640310 0.91 HCAR2 (0.32) HCAR2THRB
SCHEMBL8640311 0.91 HCAR2 (0.32) HCAR2THRB
SCHEMBL4893018 0.86 TSHR (0.35) THRB
SCHEMBL347671 0.86 TSHR (0.35) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0917554-B1 COATINGS CONTAINING FLUORINATED ESTERS DU PONT (US) 2003-02-26 EP disclosed
EP-0851903-B1 COATINGS CONTAINING FLUORINATED ESTERS DU PONT (US) 1999-06-02 EP disclosed
US-5859126-A PROTECTIVE COATING; OIL REPELLENT, WATERPROOFING; BLEND OF UNSATURATED POLYESTER, ALKYD RESIN AND POLYURETHANE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-12 US disclosed