Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.45 |
| ▸ | PPARA | Q07869 | 12/20 | 0.45 |
| ▸ | PPARD | Q03181 | 10/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938373 | 0.90 | PPARA (0.48) | PPARGPPARAPPARD | |
| SCHEMBL8816551 | 0.86 | LDHA (0.51) | PPARGPPARAPTPRB | |
| SCHEMBL27028866 | 0.86 | PPARG (0.49) | PPARGPPARAPPARDITGB3ITGA2B | |
| SCHEMBL29928639 | 0.86 | PPARG (0.49) | PPARGPPARAPPARDITGB3ITGA2B | |
| SCHEMBL6440763 | 0.80 | MEN1 (0.55) | PPARGPPARA | |
| SCHEMBL5846603 | 0.80 | MEN1 (0.55) | PPARGPPARA | |
| SCHEMBL27029034 | 0.78 | PPARA (0.49) | PPARGPPARAPPARD | |
| SCHEMBL27424457 | 0.77 | CHEK1 (0.38) | — | |
| SCHEMBL29928782 | 0.73 | PPARA (0.50) | PPARGPPARAPPARD | |
| SCHEMBL27297551 | 0.73 | PPARA (0.50) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |