SCHEMBL6938102

SCHEMBL6938102

CCOC(=O)c1ccc(OC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.79
CA12 O43570 3/20 0.79
CA1 P00915 3/20 0.79
CA2 P00918 3/20 0.79
CA7 P43166 3/20 0.79
CA9 Q16790 3/20 0.79
CA14 Q9ULX7 3/20 0.79
ESR2 Q92731 2/20 0.79
PRSS1 P07477 1/20 0.62
ACR P10323 1/20 0.62
LMNA P02545 3/20 0.60
TSHR P16473 2/20 0.60
CYP1A2 P05177 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
CYP2D6 P10635 1/20 0.60
MAPK1 P28482 1/20 0.60
CYP2C19 P33261 1/20 0.60
NR1H2 P55055 1/20 0.60
RNASEL Q05823 1/20 0.60
ALDH1A1 P00352 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14544912 0.95 ESR1 (0.72) ESR1CA12CA1CA2CA7
SCHEMBL10344282 0.93 PRSS1 (0.69) ESR1CA12CA1CA2CA7
Ethylparaben SCHEMBL5311680 0.89 CA12 (1.00) ESR1CA12CA1CA2CA7
Ethylparaben SCHEMBL28368 0.89 CA12 (1.00) ESR1CA12CA1CA2CA7
SCHEMBL5506811 0.88 ESR1 (0.82) ESR1CA12CA1CA2CA7
SCHEMBL8205439 0.88 PRSS1 (0.64) ESR1CA12CA1CA2CA7
Ethylparaben SCHEMBL23497074 0.87 CA12 (0.96) ESR1CA12CA1CA2CA7
Ethylparaben SCHEMBL475792 0.87 CA12 (0.96) ESR1CA12CA1CA2CA7
Ethylparaben SCHEMBL476012 0.87 CA12 (0.96) ESR1CA12CA1CA2CA7
Ethylparaben SCHEMBL31655760 0.87 CA12 (0.96) ESR1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3075816-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2018-05-23 EP disclosed
EP-2889358-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-10-11 EP disclosed
EP-3124573-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2017-02-01 EP disclosed
CN-101203589-A Light-duty dishwashing detergent compositions RECKITT BENCKISER INC (US) 2008-06-18 CN disclosed
US-7282245-B2 Device with multiple liquid crystal layers XEROX CORPORATION (US) 2007-10-16 US disclosed
US-7211301-B2 Liquid crystal compositions including non-dipolar monomer XEROX CORPORATION (US) 2007-05-01 US disclosed
EP-1156753-A4 TREATMENT OF TOOTH SURFACES AND SUBSTANCE THEREFOR HYGEL INC (US) 2003-05-02 EP disclosed
EP-1156753-A1 TREATMENT OF TOOTH SURFACES AND SUBSTANCE THEREFOR Hygel Inc. (US) 2001-11-28 EP disclosed
WO-2000051515-A1 TREATMENT OF TOOTH SURFACES AND SUBSTANCE THEREFOR HYGEL INC. (US) 2000-09-08 WO disclosed
US-5997301-A Treatment of tooth surfaces and substances therefor LINDEN LARS AKE (SE) 1999-12-07 US disclosed
US-5915969-A Treatment of tooth surfaces and substance therefor LINDEN LARS AAKE (SE) 1999-06-29 US disclosed