Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 1.00 |
| ▸ | CA1 | P00915 | 6/20 | 1.00 |
| ▸ | CA2 | P00918 | 6/20 | 1.00 |
| ▸ | CA7 | P43166 | 6/20 | 1.00 |
| ▸ | CA9 | Q16790 | 6/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 1.00 |
| ▸ | ESR1 | P03372 | 3/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylparaben SCHEMBL28368 | 1.00 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL29810737 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL29374744 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL29358972 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL31347872 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL23497074 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL476012 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL31655760 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL475792 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| Ethylparaben SCHEMBL29290346 | 0.98 | CA12 (0.96) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240285646-A1 | METHODS AND COMPOSITIONS FOR LIPID FORMULATION OF LIPOPHILIC SMALL MOLECULE THERAPIES OF THE HETEROCYCLIC TYPE | NEURONASCENT, INC. | 2024-08-29 | — | — | US | disclosed |
| EP-4352058-A1 | METHODS AND COMPOSITIONS FOR LIPID FORMULATION OF LIPOPHILIC SMALL MOLECULE THERAPIES OF THE HETEROCYCLIC TYPE | Neuronascent, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| EP-3054936-B1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022261404-A1 | METHODS AND COMPOSITIONS FOR LIPID FORMULATION OF LIPOPHILIC SMALL MOLECULE THERAPIES OF THE HETEROCYCLIC TYPE | NEURONASCENT, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| US-11274077-B2 | 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2022-03-15 | — | — | US | disclosed |
| US-20210323333-A1 | IMAGING MEDIUM | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2021-10-21 | — | — | US | disclosed |
| US-20210039414-A1 | IMAGING MEDIUM | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2021-02-11 | — | — | US | disclosed |
| US-20210023867-A1 | IMAGING MEDIUM | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2021-01-28 | — | — | US | disclosed |
| WO-2020117255-A1 | IMAGING MEDIA | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2020-06-11 | — | — | WO | disclosed |
| CN-104306764-B | A kind of Chinese medicine compound prescription spray for being used to control rhinitis | 昆明理工大学 | 2017-12-22 | — | — | CN | disclosed |
| CN-106543441-A | A kind of polysiloxanes side chain liquid crystalline polymer with smectic phase and preparation method thereof | 北京大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-104306764-A | Traditional Chinese medicine compound spray for treating rhinitis | UNIV KUNMING SCIENCE & TECHNOLOGY | 2015-01-28 | — | — | CN | disclosed |
| WO-2007038524-A2 | COCRYSTALLIZATION METHODS | SSCI, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| CN-1208603-A | Paraffin micro-dispersing composite and hair conditioning prepn. and finishing agent | SHISEIDO CO LTD (JP) | 1999-02-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274077-B2 | 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase | ALOX12, ALOX15, ALOX15B | CA12 3778/4885CA1 4218/4885CA2 1243/4885 |
| US-20240285646-A1 | METHODS AND COMPOSITIONS FOR LIPID FORMULATION OF LIPOPHILIC SMALL MOLECULE THERAPIES OF THE HETEROCYCLIC TYPE | NLN, SMN1; SMN2, NPC1 | CA12 4828/4885CA1 3305/4885CA2 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.