Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NMT2 | O60551 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | ADA | P00813 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326780 | 0.83 | KMT2A (0.52) | LTB4RLTB4R2KMT2AMEN1HTR6 | |
| SCHEMBL21614278 | 0.82 | CYP4F2 (0.51) | LTB4RLTB4R2KMT2AMEN1HTR6 | |
| SCHEMBL9022843 | 0.81 | LTB4R (0.84) | LTB4RLTB4R2HTR6 | |
| SCHEMBL10635313 | 0.80 | CYP4F2 (0.53) | KMT2AMEN1TRPM8PPARGPPARD | |
| SCHEMBL27386831 | 0.80 | LTB4R (0.64) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL18413804 | 0.79 | HSD17B10 (0.59) | KMT2AMEN1KDM4ERXFP1 | |
| SCHEMBL6942536 | 0.79 | MEN1 (0.54) | LTB4RLTB4R2KMT2AMEN1HTR6 | |
| SCHEMBL7901019 | 0.79 | FFAR1 (0.51) | KMT2AMEN1TRPM8PPARGPPARD | |
| SCHEMBL9023363 | 0.79 | LTB4R (0.79) | LTB4RLTB4R2 | |
| SCHEMBL23677910 | 0.79 | KMT2A (0.59) | KMT2AMEN1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |