Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SCN4A | P35499 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267463 | 0.88 | LMNA (0.68) | SCN4AKMT2AMEN1LMNAHTT | |
| SCHEMBL9663144 | 0.85 | CA1 (0.55) | CYP1A2NPC1RAB9ASCN4AKMT2A | |
| SCHEMBL14546274 | 0.84 | LMNA (0.59) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11140249 | 0.83 | CYP1A2 (0.66) | CYP1A2NPC1RAB9ASCN4AKMT2A | |
| SCHEMBL93836 | 0.82 | CYP1A2 (0.60) | CYP1A2NPC1RAB9ASCN4AKMT2A | |
| SCHEMBL17991058 | 0.82 | KDM1A (0.60) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL21194 | 0.82 | CYP1A2 (0.60) | CYP1A2NPC1RAB9ASCN4AKMT2A | |
| SCHEMBL1496562 | 0.82 | CYP1A2 (0.60) | CYP1A2NPC1RAB9ASCN4AKMT2A | |
| SCHEMBL11546333 | 0.82 | CYP1A2 (0.65) | CYP1A2PPARGPPARAKMT2AMEN1 | |
| SCHEMBL11450956 | 0.82 | MAPT (0.85) | NPC1RAB9AKMT2AMEN1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |