Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850628 | 0.90 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL15892163 | 0.90 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL10459452 | 0.89 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL19880326 | 0.89 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL17612283 | 0.88 | STING1 (0.45) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL23813544 | 0.87 | STING1 (0.56) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL9964279 | 0.87 | STING1 (0.56) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL6895355 | 0.87 | STING1 (0.56) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL1801703 | 0.87 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL14946346 | 0.87 | STING1 (0.56) | PDE4APDE4BPDE4CPDE4DADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967220-B1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6242429-B1 | ANTIVIRAL ARA-A DERIVATIVES HAVING RESISTANCE TO METABOLISM BY ADENOSINEDEAMINASE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0967220-A1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-12-29 | — | — | EP | disclosed |