SCHEMBL6938375

SCHEMBL6938375

CCCCCOOOOCCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.44
TSHR P16473 1/20 0.44
CA1 P00915 9/20 0.40
CA2 P00918 9/20 0.40
CA9 Q16790 9/20 0.40
CA12 O43570 4/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40
LPAR3 Q9UBY5 6/20 0.39
LPAR2 Q9HBW0 5/20 0.39
LPAR1 Q92633 2/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29069326 0.97 THRB (0.41) THRBTSHRCA1CA2CA9
SCHEMBL7521674 0.97 THRB (0.50) THRBTSHRCA1CA2CA9
SCHEMBL15660410 0.94 THRB (0.47) THRBTSHRCA1CA2CA9
SCHEMBL15732584 0.94 THRB (0.47) THRBTSHRCA1CA2CA9
SCHEMBL15658576 0.94 THRB (0.47) THRBTSHRCA1CA2CA9
SCHEMBL11720642 0.94 THRB (0.47) THRBTSHRCA1CA2CA9
SCHEMBL15656251 0.94 THRB (0.47) THRBTSHRCA1CA2CA9
SCHEMBL15658434 0.94 THRB (0.47) THRBTSHRCA1CA2CA9
SCHEMBL821655 0.93 THRB (0.44) THRBTSHRCA1CA2CA9
SCHEMBL11724204 0.91 THRB (0.44) THRBTSHRCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682749-B1 REDUCED FILM FORMING ANTIPERSPIRANTS AND DEODORANTS CONTAINING SILICONE ELASTOMERS COLGATE-PALMOLIVE COMPANY 2004-01-27 US disclosed
EP-1067901-B1 LOW RESIDUE COSMETIC COMPOSITION COLGATE PALMOLIVE CO (US) 2003-01-02 EP disclosed
EP-1224928-A1 Improved low residue cosmetic composition Colgate-Palmolive Company (US) 2002-07-24 EP disclosed
EP-1067901-A2 LOW RESIDUE COSMETIC COMPOSITION Colgate-Palmolive Company (US) 2001-01-17 EP disclosed
WO-1999051192-A2 LOW RESIDUE COSMETIC COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1999-10-14 WO disclosed