Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.51 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267555 | 0.87 | TDP1 (0.69) | NPC1RAB9AALOX5TDP1L3MBTL1 | |
| SCHEMBL6938948 | 0.83 | TDP1 (0.52) | NPC1RAB9ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL4032340 | 0.82 | NPC1 (0.66) | NPC1RAB9AALOX5TDP1L3MBTL1 | |
| SCHEMBL12259199 | 0.80 | FFAR1 (0.62) | NPC1RAB9AALOX5TDP1L3MBTL1 | |
| SCHEMBL24800806 | 0.79 | F2RL1 (0.74) | NPC1RAB9AALOX5TDP1L3MBTL1 | |
| SCHEMBL6208279 | 0.77 | NPC1 (0.62) | NPC1RAB9AALOX5TDP1L3MBTL1 | |
| SCHEMBL4612572 | 0.77 | NPC1 (0.74) | NPC1RAB9ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2846166 | 0.76 | TAAR1 (0.61) | NPC1RAB9ATDP1L3MBTL1F2RL1 | |
| SCHEMBL1915418 | 0.76 | HTT (0.56) | NPC1RAB9AALDH1A1F2RL1MAPT | |
| SCHEMBL27615709 | 0.76 | TDP1 (0.77) | NPC1RAB9ATDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294671-A2 | UTILISATION OF KETONES AS PRECURSORS OF ACTIVE COMPOUNDS | FIRMENICH SA (CH) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096272-A2 | UTILISATION OF KETONES AS PRECURSORS OF ACTIVE COMPOUNDS | FIRMENICH SA (CH) | 2001-12-20 | — | — | WO | disclosed |