Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 19/20 | 0.71 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941943 | 0.94 | ADA (0.71) | ADAMCL1 | |
| SCHEMBL6936415 | 0.93 | ADA (0.60) | ADABCL2MCL1 | |
| SCHEMBL6942815 | 0.92 | ADA (0.71) | ADAMCL1 | |
| SCHEMBL6941259 | 0.89 | ADA (0.71) | ADABCL2MCL1 | |
| SCHEMBL6936072 | 0.87 | ADA (0.72) | ADAMCL1 | |
| SCHEMBL6942770 | 0.87 | ADA (0.60) | ADABCL2MCL1 | |
| SCHEMBL6938565 | 0.86 | ADA (0.80) | ADA | |
| SCHEMBL6936392 | 0.85 | ADA (0.78) | ADA | |
| SCHEMBL6941269 | 0.85 | ADA (0.57) | ADAMCL1 | |
| SCHEMBL6933487 | 0.85 | ADA (0.49) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |