Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 2/20 | 0.53 |
| ▸ | FGF2 | P09038 | 2/20 | 0.53 |
| ▸ | VEGFA | P15692 | 2/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.45 |
| ▸ | CDC25B | P30305 | 8/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31103943 | 1.00 | FGF1 (0.53) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL6938614 | 1.00 | FGF1 (0.53) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL8992041 | 0.92 | SSTR1 (0.54) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL8992038 | 0.92 | SSTR1 (0.54) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL7906075 | 0.92 | SSTR1 (0.56) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL7906072 | 0.92 | SSTR1 (0.56) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL30074341 | 0.92 | SSTR1 (0.56) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL31103690 | 0.91 | FGF2 (0.44) | FGF1FGF2VEGFAHPSECA1 | |
| SCHEMBL8992084 | 0.84 | SSTR1 (0.53) | CA1CA2CA9SSTR1SSTR2 | |
| SCHEMBL8992076 | 0.84 | SSTR1 (0.53) | CA1CA2CA9SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787739-B1 | Anti-adhesive piperidine and pyrollidine -carboxylic acids | GLYCOREX AB (SE) | 2003-01-29 | — | — | EP | disclosed |
| US-5739300-A | Antiadhesive piperidine-and pyrrolidinecarboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0787739-A1 | Anti-adhesive piperidine and pyrollidine -carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-06 | — | — | EP | disclosed |