SCHEMBL6938736

SCHEMBL6938736

CC(C)CC(C)OC(=O)c1ccc(O)cc1F

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.50
CA1 P00915 7/20 0.50
CA2 P00918 7/20 0.50
CA7 P43166 7/20 0.50
CA9 Q16790 7/20 0.50
CA14 Q9ULX7 7/20 0.50
PDK2 Q15119 1/20 0.39
PDK4 Q16654 1/20 0.39
SERPINE1 P05121 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ESRRG P62508 1/20 0.38
CYP19A1 P11511 1/20 0.37
LMNA P02545 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
HSP90AB1 P08238 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6938740 1.00 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL6547031 0.89 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL6547027 0.89 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL7609522 0.88 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL7609521 0.88 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL9344940 0.81 ALDH1A1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL7120872 0.81 ALDH1A1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL7120866 0.81 ALDH1A1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL8610288 0.81 ALDH1A1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL6937264 0.80 PRSS1 (0.42) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0978504-B1 Anti-ferroelectric liquid crystal compound MITSUBISHI GAS CHEMICAL CO (JP) 2003-07-02 EP disclosed
US-6133469-A HIGH PERFORMANCE LIQUID CRYSTAL DISPLAY DEVICES HAVING LARGER DISPLAY CAPACITY MITSUBISHI GAS CHEMICAL COMPANY (JP) 2000-10-17 US disclosed
JP-2000109450-A ANTIFERROELECTRIC LIQUID CRYSTAL COMPOUND MITSUBISHI GAS CHEM CO INC 2000-04-18 JP disclosed
EP-0978504-A1 Anti-ferroelectric liquid crystal compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-02-09 EP disclosed