Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.55 |
| ▸ | YWHAG | P61981 | 1/20 | 0.55 |
| ▸ | YWHAZ | P63104 | 1/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | P2RX5 | Q93086 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26180887 | 0.80 | P2RX7 (0.52) | P2RX7YWHAGYWHAZP2RX2ESR1 | |
| SCHEMBL30621209 | 0.80 | P2RX7 (0.52) | P2RX7YWHAGYWHAZP2RX2ESR1 | |
| SCHEMBL26180896 | 0.76 | P2RX7 (0.48) | P2RX7YWHAGYWHAZP2RX2ESR1 | |
| SCHEMBL30621214 | 0.76 | P2RX7 (0.48) | P2RX7YWHAGYWHAZP2RX2ESR1 | |
| SCHEMBL7093516 | 0.73 | P2RX7 (0.83) | P2RX7YWHAGYWHAZP2RX2MAPT | |
| SCHEMBL7090990 | 0.73 | P2RX7 (0.74) | P2RX7YWHAGYWHAZP2RX2MAPT | |
| SCHEMBL4934793 | 0.73 | P2RX7 (0.60) | P2RX7YWHAGYWHAZP2RX2ESR1 | |
| SCHEMBL25271476 | 0.71 | P2RX7 (1.00) | P2RX7YWHAGYWHAZP2RX2MAPT | |
| SCHEMBL14702229 | 0.71 | P2RX7 (1.00) | P2RX7YWHAGYWHAZP2RX2MAPT | |
| SCHEMBL32686684 | 0.71 | P2RX7 (1.00) | P2RX7YWHAGYWHAZP2RX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030101005-A1 | Crystals and structures of perosamine synthase homologs | STRUCTURAL GENOMIX, INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003006617-A2 | CRYSTALS AND STRUCTURES OF PEROSAMINE SYNTHASE HOMOLOGS | STRUCTURAL GENOMIX, INC. (US) | 2003-01-23 | — | — | WO | disclosed |