Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572917 | 0.72 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL1549079 | 0.68 | — | — | |
| SCHEMBL2635389 | 0.67 | — | — | |
| SCHEMBL27916845 | 0.63 | — | — | |
| SCHEMBL15913583 | 0.62 | — | — | |
| SCHEMBL15924450 | 0.62 | — | — | |
| SCHEMBL31170982 | 0.62 | — | — | |
| SCHEMBL10863578 | 0.61 | — | — | |
| SCHEMBL28965726 | 0.61 | HTT (0.32) | — | |
| SCHEMBL27767371 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983064-B1 | PYRROLES AS sPLA2 INHIBITORS | LILLY CO ELI (US) | 2003-08-06 | — | — | EP | disclosed |
| EP-0983064-A4 | PYRROLES AS sPLA2 INHIBITORS | LILLY CO ELI (US) | 2001-01-31 | — | — | EP | disclosed |
| EP-0983064-A1 | PYRROLES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| US-5919774-A | NOVEL COMPOUNDS SUCH AS 2-(1-BENZYL-2,5-DIMETHYL-4-(2-CARBOXYPHENYLMETHYL)PYRROL-3-YL) GLYOXAMIDE FOR INHIBITING HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE A2 (SPLA2) MEDIATED RELEASE OF FATTY ACIDS IN A MAMMAL | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1998025609-A1 | PYRROLES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |