Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7873982 | 0.98 | MAPT (0.55) | ALOX15MAPTPKMKMT2AADRA2A | |
| SCHEMBL6938671 | 0.79 | KMT2A (0.54) | ALOX15MAPTPKMKMT2AADRA2A | |
| SCHEMBL6940699 | 0.76 | ADRA2A (0.44) | ALOX15MAPTKMT2AADRA2AADRA2B | |
| SCHEMBL6939241 | 0.76 | ADRA2A (0.44) | ALOX15MAPTKMT2AADRA2AADRA2B | |
| SCHEMBL4098831 | 0.76 | KMT2A (0.62) | ALOX15MAPTPKMKMT2AADRA2A | |
| SCHEMBL6935250 | 0.75 | ADRA2A (0.57) | ALOX15KMT2AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7866932 | 0.74 | ADRA2A (0.56) | ALOX15MAPTKMT2AADRA2AADRA2B | |
| SCHEMBL6937198 | 0.70 | ADRA2A (0.59) | ALOX15KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL1669960 | 0.69 | ADRA2A (0.56) | ALOX15MAPTPKMKMT2AADRA2A | |
| Hydrochloric Acid SCHEMBL7869920 | 0.69 | ADRA2A (0.58) | ALOX15MAPTKMT2AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101756-B1 | Aminopyrrolidine derivatives, processes for their preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-1101756-A1 | Aminopyrrolidine derivatives, processes for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-05-23 | — | — | EP | disclosed |