Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.68 |
| ▸ | NAMPT | P43490 | 3/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.65 |
| ▸ | F3 | P13726 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413773 | 0.90 | HDAC1 (0.65) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL2409819 | 0.84 | HDAC1 (0.72) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL2413513 | 0.83 | HDAC1 (0.77) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL2412421 | 0.83 | HDAC1 (0.84) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL2413377 | 0.82 | HDAC1 (0.78) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL1063181 | 0.82 | HDAC1 (0.67) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL28405903 | 0.81 | HDAC1 (1.00) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL2415852 | 0.81 | HDAC1 (0.92) | HDAC1NAMPTHDAC3HDAC2HDAC4 | |
| SCHEMBL6944020 | 0.81 | PKM (0.66) | NAMPTCYP3A4HTTLMNAKMT2A | |
| SCHEMBL2419301 | 0.81 | HDAC1 (0.60) | HDAC1NAMPTHDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974576-B1 | Method of producing benzamide derivatives | MITSUI CHEMICALS INC (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6320078-B1 | CONVERTING BENZOIC ACID DERIVATIVE INTO BENZOYLIMIDAZOLE DERIVATIVE, REACTING BENZOYLIMIDAZOLE DERIVATIVE WITH PHENYLENEDIAMINE DERIVATIVE TO PREPARE SELECTIVELY MONOACYLATED PHENYLENEDIAMINE DERIVATIVE | MITSUI CHEMICALS, INC. (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0974576-A2 | Method of producing benzamide derivatives | Mitsui Chemicals, Inc. (JP) | 2000-01-26 | — | — | EP | disclosed |