Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.42 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075397 | 0.81 | SLC1A1 (0.45) | SLC1A1KMT2AFOLH1CTSSALDH1A1 | |
| SCHEMBL1195693 | 0.80 | KMT2A (0.49) | SLC1A1KMT2AFOLH1CTSLCTSS | |
| SCHEMBL4906646 | 0.80 | KMT2A (0.49) | SLC1A1KMT2AFOLH1CTSLCTSS | |
| SCHEMBL4909047 | 0.80 | KMT2A (0.49) | SLC1A1KMT2AFOLH1CTSLCTSS | |
| SCHEMBL13535255 | 0.79 | SLC1A1 (0.48) | SLC1A1KMT2AFOLH1MIFMAPT | |
| SCHEMBL13535259 | 0.78 | SLC1A1 (0.50) | SLC1A1KMT2AMAPTALDH1A1CA1 | |
| SCHEMBL30231867 | 0.77 | CA1 (0.51) | SLC1A1KMT2AFOLH1MIFALDH1A1 | |
| SCHEMBL13733023 | 0.77 | CA1 (0.51) | SLC1A1KMT2AFOLH1MIFALDH1A1 | |
| SCHEMBL29097257 | 0.77 | CA1 (0.51) | SLC1A1KMT2AFOLH1MIFALDH1A1 | |
| SCHEMBL13733029 | 0.77 | CA1 (0.51) | SLC1A1KMT2AFOLH1MIFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |