Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Norflurane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6956243 | 0.81 | — | — | |
| Norflurane SCHEMBL5530396 | 0.80 | — | — | |
| Trifluoroethanol SCHEMBL3132268 | 0.80 | — | — | |
| Norflurane SCHEMBL28114842 | 0.79 | — | — | |
| Norflurane SCHEMBL15539999 | 0.79 | — | — | |
| Norflurane SCHEMBL5466910 | 0.78 | — | — | |
| Norflurane SCHEMBL11036325 | 0.78 | — | — | |
| Norflurane SCHEMBL1173735 | 0.78 | — | — | |
| Norflurane SCHEMBL9499 | 0.78 | — | — | |
| Norflurane SCHEMBL8763817 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226006-A1 | PHARMACEUTICAL AEROSOL PRODUCT FOR ADMINISTRATION BY ORAL OR NASAL INHALATION | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2024-07-11 | — | — | US | claimed |
| US-11007150-B2 | Pharmaceutical aerosol product for administration by oral or nasal inhalation | COVIS PHARMA GMBH (CH) | 2021-05-18 | — | — | US | claimed |
| EP-0983058-B1 | MEDICINAL AEROSOL PRODUCTS | MINNESOTA MINING & MFG (US) | 2003-07-30 | — | — | EP | claimed |
| US-20240226006-A1 | PHARMACEUTICAL AEROSOL PRODUCT FOR ADMINISTRATION BY ORAL OR NASAL INHALATION | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2024-07-11 | — | — | US | disclosed |
| US-11992556-B2 | Pharmaceutical aerosol product for administration by oral or nasal inhalation | COVIS PHARMA GMBH (CH) | 2024-05-28 | — | — | US | disclosed |
| US-11007150-B2 | Pharmaceutical aerosol product for administration by oral or nasal inhalation | COVIS PHARMA GMBH (CH) | 2021-05-18 | — | — | US | disclosed |
| CN-102145044-B | Compound spray for treating cardiovascular and cerebrovascular diseases and preparation method of compound spraying | TIANSHENG PHARMACEUTICAL GROUP CO LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-102145044-A | Compound spray for treating cardiovascular and cerebrovascular diseases and preparation method of compound spraying | TIANSHENG PHARMACEUTICAL GROUP CO LTD | 2011-08-10 | — | — | CN | disclosed |