Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propanol SCHEMBL9236962 | 0.87 | ALDH1A1 (0.35) | — | |
| Methyl Alcohol SCHEMBL365291 | 0.85 | — | — | |
| SCHEMBL7111729 | 0.84 | — | — | |
| SCHEMBL9852 | 0.84 | — | — | |
| Norflurane SCHEMBL6940064 | 0.81 | — | — | |
| SCHEMBL18759839 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL12492362 | 0.81 | — | — | |
| SCHEMBL2508332 | 0.81 | — | — | |
| Bromide SCHEMBL28366174 | 0.81 | — | — | |
| Water SCHEMBL525261 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278973-A1 | CRYSTAL FORMS OF TETRAHYDRO-N, N-DIMETHYL-2, 2-DIPHENYL-3-FURANMETHANAMINE, PROCESSES OF MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS | ANAVEX LIFE SCIENCES CORP (US) | 2023-09-07 | — | — | US | claimed |
| US-11661405-B2 | Crystal forms of tetrahydro-n,n-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride, processes of making such forms, and their pharmaceutical compositions | ANAVEX LIFE SCIENCES CORP. (US) | 2023-05-30 | — | — | US | claimed |
| US-20210220321-A1 | CRYSTAL FORMS OF TETRAHYDRO-N,N-DIMETHYL-2,2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES OF MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS | ANAVEX LIFE SCIENCES CORP. (US) | 2021-07-22 | — | — | US | claimed |
| EP-2496565-B1 | Process for preparing divinylarene dioxides | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-08-13 | — | — | EP | claimed |
| EP-0394927-B1 | Process for preparing methacrylates of fluorinated alcohols | AUSIMONT SPA (IT) | 1993-12-08 | — | — | EP | claimed |
| EP-0130052-B1 | FLUORINATED VINYL ETHER COPOLYMERS HAVING LOW GLASS TRANSITION TEMPERATURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0010150-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING SUBSTITUENT GROUPS WHICH ARE PENDENTLY BONDED TO PHOSPHORUS THROUGH NITROGEN AND PROCESS FOR THEIR PREPARATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-07-20 | — | — | EP | claimed |
| EP-0010590-B1 | POLYPHOSPHAZENE COPOLYMERS CONTAINING A SUBSTITUENT BONDED TO PHOSPHORUS THROUGH A CARBON ATOM, AND THEIR PREPARATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-01-12 | — | — | EP | claimed |
| EP-0016249-B1 | POLYPHOSPHAZENE COPOLYMERS CONTAINING DIALKYL AMINOXY SUBSTITUENTS, AND PROCESS FOR PRODUCING THEM | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-12-15 | — | — | EP | claimed |
| US-20230278973-A1 | CRYSTAL FORMS OF TETRAHYDRO-N, N-DIMETHYL-2, 2-DIPHENYL-3-FURANMETHANAMINE, PROCESSES OF MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS | ANAVEX LIFE SCIENCES CORP (US) | 2023-09-07 | — | — | US | disclosed |
| US-11661405-B2 | Crystal forms of tetrahydro-n,n-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride, processes of making such forms, and their pharmaceutical compositions | ANAVEX LIFE SCIENCES CORP. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210220321-A1 | CRYSTAL FORMS OF TETRAHYDRO-N,N-DIMETHYL-2,2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES OF MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS | ANAVEX LIFE SCIENCES CORP. (US) | 2021-07-22 | — | — | US | disclosed |
| US-10966952-B2 | Crystal forms of tetrahydro-n,n-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride, processes of making such forms, and their pharmaceutical compositions | ANAVEX LIFE SCIENCES CORP. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190350892-A1 | CRYSTAL FORMS OF TETRAHYDRO-N,N-DIMETHYL-2,2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES OF MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS | ANAVEX LIFE SCIENCES CORP. (US) | 2019-11-21 | — | — | US | disclosed |
| EP-1104758-B1 | Acetylene derivatives as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6538009-B2 | Selective cyclooxygenase-2 (COX-2) inhibitors; for example, 1-(5-Methanesulfonyl-pyridin-2-yl)-7-methoxy-3-trifluoromethyl-4,5-dihydro -1H-benzo(g) indazole | PFIZER, INC. | 2003-03-25 | — | — | US | disclosed |
| US-6506779-B1 | useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock. | PFIZER INC. | 2003-01-14 | — | — | US | disclosed |
| US-20020115856-A1 | Pyrazole derivatives as anti-inflammatory/analgesic agents | SAKYA SUBAS MAN (US) | 2002-08-22 | — | — | US | disclosed |
| EP-1142889-A1 | Pyrazole derivatives as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1104758-A1 | Acetylene derivatives as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |