Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31041689 | 0.94 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1ALOX15MAPK1PKM | |
| SCHEMBL12164343 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1ALOX15MAPK1PKM | |
| SCHEMBL314073 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1ALOX15MAPK1PKM | |
| SCHEMBL2513477 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1ALOX15PKMRAB9A | |
| SCHEMBL8381260 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1ALOX15PKMRAB9A | |
| SCHEMBL7991194 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1ALOX15MAPK1PKM | |
| SCHEMBL14423917 | 0.76 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1ALOX15MAPK1PKM | |
| SCHEMBL20749127 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1ALOX15PKMKMT2A | |
| SCHEMBL68781 | 0.76 | — | — | |
| SCHEMBL8118694 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1ALOX15PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038286-B1 | PYRRO[1,2-B]PYRIDAZINONE COMPOUNDS | ANADYS PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-1309533-A1 | PRODUCTION OF 3-ALKYLCYCLOALKANOLS | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2003-05-14 | — | — | EP | disclosed |
| EP-1309529-A1 | FRAGRANCE COMPOUNDS | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014243-A1 | NOVEL FRAGRANCE COMPOUNDS | QUEST INTERNATIONAL B.V. (NL) | 2002-02-21 | — | — | WO | disclosed |
| WO-2002014253-A1 | CYCLOHEXYL ETHERS AS FRAGRANCE COMPOUNDS | QUEST INTERNATIONAL B.V. (NL) | 2002-02-21 | — | — | WO | disclosed |
| WO-2002014255-A1 | PRODUCTION OF 3-ALKYLCYCLOALKANOLS | QUEST INTERNATIONAL B.V. (NL) | 2002-02-21 | — | — | WO | disclosed |