SCHEMBL6940120

SCHEMBL6940120

CC(=O)NNCCC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 2/20 0.51
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 2/20 0.45
RAB9A P51151 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
CCNB2 O95067 1/20 0.43
CCNE2 O96020 1/20 0.43
CDK1 P06493 1/20 0.43
CDK4 P11802 1/20 0.43
CCNB1 P14635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7773309 0.98 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL24526798 0.86 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL7773331 0.86 HTT (0.55) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
Hydrochloric Acid SCHEMBL7773347 0.84 HTT (0.54) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL645952 0.83 HDAC3 (0.53) ALDH1A1MAPK1L3MBTL1KMT2AMEN1
SCHEMBL5214847 0.82 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL13323438 0.82 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL644883 0.81 SYK (0.50) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL10200841 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL13139870 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6538007-B1 Hydrates and method of antogonizing glycoprotein IIb/IIIa activity using these compounds is also disclosed. antagonist, inhibitor of blood platelets aggregation and inhibitor of the binding of fibrinogen to blood platelets. FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-03-25 US disclosed
EP-1121346-A1 NEW PROCESSES FOR PRODUCING BETA-ALANINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-08-08 EP disclosed
WO-2000021932-A1 NEW PROCESSES FOR PRODUCING β-ALANINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-04-20 WO disclosed