Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 4/20 | 0.58 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940189 | 0.94 | ESR1 (0.65) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289842 | 0.91 | ESR1 (0.69) | PLA2G2AESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29263833 | 0.91 | ESR1 (0.69) | PLA2G2AESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL27673441 | 0.85 | ESR1 (0.64) | PLA2G2AESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL3777659 | 0.85 | ESR1 (0.64) | PLA2G2AESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28583778 | 0.85 | ESR1 (0.63) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27893069 | 0.85 | ESR1 (0.67) | PLA2G2AESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL23250535 | 0.84 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289827 | 0.84 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289817 | 0.84 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |