Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 13/20 | 0.72 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939093 | 0.90 | ADA (0.67) | ADATAAR1MEN1KMT2A | |
| SCHEMBL6133731 | 0.84 | ADA (1.00) | ADA | |
| SCHEMBL6938971 | 0.83 | ADA (0.70) | ADATAAR1JAK3 | |
| Hydrochloric Acid SCHEMBL6133941 | 0.83 | ADA (0.98) | ADA | |
| SCHEMBL6172584 | 0.77 | ADA (0.72) | ADA | |
| SCHEMBL6170497 | 0.75 | ADA (0.84) | ADA | |
| SCHEMBL6133735 | 0.73 | ADA (0.59) | ADATAAR1SCN9A | |
| Hydrochloric Acid SCHEMBL6133945 | 0.72 | ADA (0.58) | ADATAAR1SCN9A | |
| SCHEMBL6168422 | 0.72 | ADA (0.68) | ADAMEN1KMT2A | |
| SCHEMBL6940309 | 0.70 | ADA (0.53) | ADATAAR1JAK3SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |