Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.44 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | DRD1 | P21728 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794599 | 0.76 | ESR2 (0.49) | ESR2ESR1DRD2DRD1CA1 | |
| SCHEMBL6799659 | 0.73 | DRD2 (0.45) | ESR2ESR1DRD2DRD1DRD5 | |
| SCHEMBL6801258 | 0.69 | DRD1 (0.47) | ESR2ESR1DRD2DRD1DRD5 | |
| SCHEMBL6799175 | 0.69 | DRD1 (0.47) | ESR2ESR1DRD2DRD1DRD5 | |
| SCHEMBL21326866 | 0.65 | DRD2 (0.40) | ESR2ESR1DRD2DRD1CA1 | |
| SCHEMBL6796118 | 0.65 | ESR1 (0.42) | ESR2ESR1DRD2DRD1DRD5 | |
| SCHEMBL6797459 | 0.65 | DRD2 (0.43) | ESR2ESR1DRD2DRD1DRD5 | |
| SCHEMBL11205264 | 0.65 | DRD1 (0.69) | ESR2ESR1DRD2DRD1CA1 | |
| SCHEMBL31634361 | 0.65 | DRD1 (0.69) | ESR2ESR1DRD2DRD1CA1 | |
| Bromide SCHEMBL21326962 | 0.64 | ESR1 (0.39) | ESR2ESR1DRD2DRD1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339662-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046134-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2002-06-13 | — | — | WO | disclosed |