Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 10/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962141 | 1.00 | HSP90AB1 (0.38) | HSP90AB1HSP90AA1HRH4HDAC1HDAC2 | |
| SCHEMBL10510295 | 0.87 | HDAC1 (0.44) | HSP90AB1HSP90AA1HRH4HDAC1HDAC2 | |
| SCHEMBL1663919 | 0.84 | HDAC1 (0.43) | HSP90AB1HSP90AA1HRH4HDAC1HDAC2 | |
| SCHEMBL1663924 | 0.84 | HDAC1 (0.43) | HSP90AB1HSP90AA1HRH4HDAC1HDAC2 | |
| SCHEMBL1663801 | 0.84 | HDAC1 (0.43) | HSP90AB1HSP90AA1HRH4HDAC1HDAC2 | |
| SCHEMBL8618199 | 0.75 | HSP90AB1 (0.38) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL8542896 | 0.75 | HSP90AB1 (0.38) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL15496830 | 0.74 | HDAC1 (0.42) | HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL16039115 | 0.73 | HSP90AA1 (0.39) | HSP90AB1HSP90AA1HRH4HDAC1HDAC2 | |
| SCHEMBL10496728 | 0.73 | DAPK1 (0.49) | HRH4HDAC6CYP1A2ADORA2ATMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822817-B1 | USE OF (R)-PENCICLOVIR TRIPHOSPHATE FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF VIRAL DISEASES | NOVARTIS INT PHARM LTD (BM) | 2003-07-23 | — | — | EP | disclosed |