Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 17/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542896 | 1.00 | HSP90AB1 (0.38) | HSP90AB1HSP90AA1HDAC1HDAC2HSP90B1 | |
| SCHEMBL6940477 | 0.75 | HSP90AB1 (0.38) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL5962141 | 0.75 | HSP90AB1 (0.38) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL10510295 | 0.73 | HDAC1 (0.44) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL1663919 | 0.72 | HDAC1 (0.43) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL1663801 | 0.72 | HDAC1 (0.43) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL1663924 | 0.72 | HDAC1 (0.43) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL28434898 | 0.71 | KDM4E (0.54) | HSP90AB1HSP90AA1HDAC1HSP90B1TRAP1 | |
| SCHEMBL16039115 | 0.67 | HSP90AA1 (0.39) | HSP90AB1HSP90AA1HDAC1HDAC2HDAC6 | |
| SCHEMBL3856260 | 0.67 | HSP90AB1 (0.40) | HSP90AB1HSP90AA1HDAC1HDAC2HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822817-A1 | USE OF (R)-PENCICLOVIR TRIPHOSPHATE FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF VIRAL DISEASES | SMITHKLINE BEECHAM PLC (GB) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033720-A1 | USE OF (R)-PENCICLOVIR TRIPHOSPHATE FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF VIRAL DISEASES | SMITHKLINE BEECHAM PLC (GB) | 1996-10-31 | — | — | WO | disclosed |