Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170541 | 0.87 | PRSS1 (0.51) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL27490729 | 0.83 | ALDH1A1 (0.49) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL2292810 | 0.82 | PRSS1 (0.54) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL27314977 | 0.81 | PRSS1 (0.53) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL2294567 | 0.81 | PRSS1 (0.56) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL9410807 | 0.81 | PRSS1 (0.52) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL44568 | 0.80 | PRSS1 (0.62) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL43233 | 0.80 | PRSS1 (0.67) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL2987920 | 0.80 | PRSS1 (0.51) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL666850 | 0.80 | ALDH1A1 (0.48) | PRSS1PRSS2PRSS3EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |