Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18430563 | 1.00 | AKR1C3 (0.57) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL11377632 | 0.83 | AKR1C3 (0.53) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL11377680 | 0.83 | AKR1C3 (0.53) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL1081471 | 0.82 | AKR1C3 (0.56) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL181651 | 0.82 | MCL1 (0.52) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL792779 | 0.82 | AKR1C3 (0.56) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL20049735 | 0.82 | MCL1 (0.57) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL17397066 | 0.82 | MCL1 (0.57) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL5982913 | 0.82 | AKR1C3 (0.56) | AKR1C3RECQLALDH1A1TSHRMCL1 | |
| SCHEMBL11594648 | 0.82 | MCL1 (0.57) | AKR1C3RECQLALDH1A1TSHRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127581-A | Method for the preparation of 3-phenyl-5-substituted-4(1H)-pyridones | ELI LILLY AND COMPANY (US) | 1978-11-28 | — | — | US | claimed |
| CN-104109218-B | （Methyl）Acrylic ester polymer, composition containing the polymer and application thereof | 昭和电工株式会社 | 2018-06-12 | — | — | CN | disclosed |
| CN-103787912-A | Preparation method of benzylidene acetone amine derivative antiknock agent | NINGXIA BAOTA PETROCHEMICAL TECHNOLOGY INDUSTRY DEV CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-103787912-A | Preparation method of benzylidene acetone amine derivative antiknock agent | NINGXIA BAOTA PETROCHEMICAL TECHNOLOGY INDUSTRY DEV CO LTD | 2014-05-14 | — | — | CN | disclosed |
| EP-1228034-A4 | CHIRAL PHOSPHINES, TRANSITION METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | PENN STATE RES FOUND (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1228034-A2 | CHIRAL PHOSPHINES, TRANSITION METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001034612-A2 | CHIRAL PHOSPHINES, TRANSITION METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-05-17 | — | — | WO | disclosed |
| US-4127581-A | Method for the preparation of 3-phenyl-5-substituted-4(1H)-pyridones | ELI LILLY AND COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4127581-A | Method for the preparation of 3-phenyl-5-substituted-4(1H)-pyridones | ELI LILLY AND COMPANY (US) | 1978-11-28 | — | — | US | disclosed |