⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993741 | 0.79 | ALDH1A1 (0.69) | — | |
| SCHEMBL4100191 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL6363153 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL9806977 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL1844531 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL29084539 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL2856429 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL11482159 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL19501744 | 0.76 | ALDH1A1 (0.64) | — | |
| SCHEMBL28786 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | claimed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | claimed |
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5583218-A | ANTIBIOTICS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0368259-B1 | Carbapenem derivatives | DAIICHI SEIYAKU CO (JP) | 1994-07-20 | — | — | EP | disclosed |
| EP-0368259-A1 | Carbapenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |