Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.70 |
| ▸ | IAPP | P10997 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940708 | 1.00 | APP (0.70) | APPIAPPHTR1AP4HBTOP2A | |
| SCHEMBL7316471 | 0.83 | APP (0.59) | APPIAPPHTR1ATOP2AMAOA | |
| SCHEMBL7316473 | 0.83 | APP (0.59) | APPIAPPHTR1ATOP2AMAOA | |
| SCHEMBL547240 | 0.83 | APP (0.66) | APPIAPPHTR1AHSP90AA1 | |
| SCHEMBL9019324 | 0.83 | APP (0.66) | APPIAPPHTR1AHSP90AA1 | |
| SCHEMBL3398186 | 0.83 | APP (0.66) | APPIAPPHTR1AHSP90AA1 | |
| SCHEMBL157815 | 0.83 | APP (0.66) | APPIAPPHTR1AHSP90AA1 | |
| SCHEMBL17746768 | 0.83 | APP (0.66) | APPIAPPHTR1AHSP90AA1 | |
| SCHEMBL10954039 | 0.83 | APP (0.66) | APPIAPPHTR1AHSP90AA1 | |
| SCHEMBL8847657 | 0.83 | APP (0.66) | APPIAPPHTR1ATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050528-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6335367-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC | 2002-01-01 | — | — | US | disclosed |
| EP-1050528-A1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | ROHM AND HAAS COMPANY (US) | 2000-11-08 | — | — | EP | disclosed |