Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 16/20 | 0.44 |
| ▸ | METAP1 | P53582 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478013 | 0.76 | METAP2 (0.53) | METAP2METAP1 | |
| SCHEMBL6477096 | 0.75 | METAP2 (0.52) | METAP2METAP1 | |
| SCHEMBL6477252 | 0.71 | METAP2 (0.66) | METAP2METAP1 | |
| SCHEMBL6489481 | 0.71 | METAP2 (0.50) | METAP2METAP1 | |
| SCHEMBL6935912 | 0.71 | METAP2 (0.42) | METAP2METAP1 | |
| SCHEMBL6476471 | 0.70 | METAP2 (0.49) | METAP2METAP1 | |
| SCHEMBL6245482 | 0.67 | METAP2 (0.56) | METAP2METAP1 | |
| SCHEMBL5848309 | 0.67 | METAP2 (0.56) | METAP2METAP1 | |
| SCHEMBL5849991 | 0.67 | METAP2 (0.56) | METAP2METAP1 | |
| SCHEMBL6477893 | 0.66 | METAP2 (0.47) | METAP2METAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |