SCHEMBL694106

SCHEMBL694106

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2c(C)cccc2C(=O)O)n1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 1/20 0.36
CDK1 P06493 1/20 0.36
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28384535 0.92 GAA (0.41) GAAALDH1A1SMN1; SMN2KMT2AKDM4E
SCHEMBL11374847 0.88 GAA (0.44) GAAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL6313355 0.86 GAA (0.57) GAASMN1; SMN2MAPTKMT2ACDK1
SCHEMBL66269 0.85 MAPT (0.46) GAAALDH1A1MAPTKDM4ENPC1
SCHEMBL29396197 0.85 MAPT (0.46) GAAALDH1A1MAPTKDM4ENPC1
SCHEMBL30013512 0.85 MAPT (0.46) GAAALDH1A1MAPTKDM4ENPC1
SCHEMBL6061971 0.84 GAA (0.38) GAAALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL21462144 0.84 MAPT (0.46) GAAALDH1A1MAPTKDM4ENPC1
SCHEMBL9136178 0.83 MAPT (0.41) GAAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL8793442 0.83 MAPT (0.43) GAAALDH1A1SMN1; SMN2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901753-B1 HERBICIDAL COMPOSITION UBE INDUSTRIES (JP) 2004-04-28 EP claimed
EP-0575489-B1 WATER-DISPERSIBLE GRANULAR AGRICULTURAL COMPOSITIONS MADE BY HEAT EXTRUSION DU PONT (US) 1997-07-02 EP claimed
EP-0637909-B1 REVERSIBLE AGRICULTURAL GEL AND PASTE FORMULATIONS DU PONT (US) 1997-02-26 EP claimed
EP-0619946-B1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO LTD (JP) 1996-06-05 EP claimed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
US-5441923-A Water-soluble or water dispersible pesticide granules comprising sulfonylurea herbicides in a polyethylene or polypropylene coating E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-15 US claimed
EP-0471284-B1 Herbicidal compositions IDEMITSU KOSAN CO (JP) 1995-01-18 EP claimed
US-5369022-A Plant saftening agents for corn or wheat crops by genetic resistance AMERICAN CYANAMID COMPANY (US) 1994-11-29 US claimed
EP-0422026-B1 TABLET FORMULATIONS OF PESTICIDES DU PONT (US) 1994-09-07 EP claimed
EP-0360441-B1 Water-soluble or water-dispersible pesticide granules DU PONT (US) 1994-04-27 EP claimed
EP-0275555-B1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-05-13 EP claimed
EP-0298901-B1 HERBICIDAL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-15 EP claimed
EP-0375875-A2 A method to improve the protection of crops from herbicidal injury AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP claimed
EP-0360441-A1 Water-soluble or water-dispersible pesticide granules E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-28 EP claimed
US-4818278-A N-/HETEROCYCLICAMINOCARBONYL/ARYL SULFONAMIDES; HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-04 US claimed
EP-0298901-A2 Herbicidal agents HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-11 EP claimed
JP-1034903-A None JP disclosed
JP-5229907-A None JP disclosed
EP-0275555-A2 Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-07-27 EP disclosed
JP-S06434903-A 0001-01-01 JP disclosed