Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66269 | 0.89 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL30013512 | 0.89 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL29396197 | 0.89 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL21462144 | 0.89 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL8507303 | 0.88 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ENPC1GAA | |
| Metsulfuron-Methyl SCHEMBL9451064 | 0.86 | NPC1 (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| Iodosulfuron SCHEMBL19463106 | 0.85 | MAPT (0.41) | MAPTALDH1A1KDM4ENPC1GAA | |
| Chlorsulfuron SCHEMBL3428108 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL29489600 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL29360781 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ENPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |