Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936318 | 0.97 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL1237922 | 0.82 | TSHR (0.36) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL35205 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL27866453 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL10776617 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL28252231 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL9861711 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL27533403 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL29188645 | 0.76 | TSHR (0.45) | ALDH1A1TSHRPTGS1THRBMEN1 | |
| SCHEMBL4759428 | 0.76 | TSHR (0.52) | ALDH1A1TSHRHSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |