3-Methyl-2-Phenyl-4H-Chromen-4-One

3-Methyl-2-Phenyl-4H-Chromen-4-One

SCHEMBL694139

Cc1c(-c2ccccc2)oc2ccccc2c1=O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.68
CYP3A4 P08684 6/20 0.68
TSHR P16473 2/20 0.68
CYP2C9 P11712 1/20 0.68
CYP2C19 P33261 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
ABCG2 Q9UNQ0 2/20 0.66
KDM4E B2RXH2 7/20 0.65
KMT2A Q03164 5/20 0.65
MEN1 O00255 4/20 0.65
LMNA P02545 3/20 0.65
TP53 P04637 2/20 0.65
ALOX15 P16050 2/20 0.65
MAPK1 P28482 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
DDR2 Q16832 1/20 0.65
CA12 O43570 1/20 0.65
ABCB1 P08183 1/20 0.65
CALM1 P0DP23 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8607746 0.90 TSHR (0.72) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL27406417 0.87 DDR2 (0.58) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL311968 0.87 CYP3A4 (0.72) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL10022780 0.85 TNKS (0.57) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL2620726 0.85 ABCG2 (0.54) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL29839908 0.85 ABCG2 (0.54) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL27404210 0.84 ABCG2 (0.76) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL31316450 0.83 MAPT (0.74) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL29171535 0.83 MAPT (0.74) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19
SCHEMBL29349443 0.81 KMT2A (0.69) ALDH1A1CYP3A4TSHRCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119470756-A UPLC quantitative fingerprint detection method for camphor head red tangerine peel 赣江中药创新中心 2025-02-18 CN claimed
CN-118930508-A Synthesis process of flavone methylphenidate hydrochloride 平顶山隆维生物科技有限公司 2024-11-12 CN claimed
CN-118161528-A Orange juice flavone carbon dots and application thereof in hyposensitization skin contact material 吉林大学 2024-06-11 CN claimed
CN-113956994-B Two bacterial strains capable of breaking carbon glycoside bond of flavonoid carbon glycoside compound and application thereof 北京中医药大学 2023-09-15 CN claimed
CN-112961870-B Carbon glycosyltransferase DhCGT2 gene in pseudo-ginseng plant and application thereof 云南农业大学 2022-08-16 CN claimed
CN-112813084-B Carbon glycosyltransferase DhCGT1 gene in pseudo-anethod plants and application thereof 云南农业大学 2022-07-19 CN claimed
CN-113956994-A Two bacterial strains capable of breaking carbon-glycoside bonds of flavonoid carbon glycoside compounds and application thereof 北京中医药大学 2022-01-21 CN claimed
CN-113956226-A Method for synthesizing carvachin 南京科技职业学院 2022-01-21 CN claimed
CN-113322288-A Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycosides and application thereof 中国科学院分子植物科学卓越创新中心 2021-08-31 CN claimed
CN-112294794-B Application of methyl ophiopogonone A in preparation of medicine for preventing and/or treating non-alcoholic fatty liver disease and liver injury 四川大学 2021-07-30 CN claimed
CN-112813084-A Carbon glycosyltransferase DhCGT1 gene in pseudo-ginseng plant and application thereof 云南农业大学 2021-05-18 CN claimed
CN-112294794-A Application of methyl ophiopogonone A in preparation of medicine for preventing and/or treating non-alcoholic fatty liver disease and liver injury 四川大学 2021-02-02 CN claimed
CN-107821646-A One kind improves three high linseed oil and preparation method thereof 余雪平 2018-03-23 CN claimed
EP-2421823-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS Janssen Pharmaceutica N.V. (BE) 2012-02-29 EP claimed
WO-2010124086-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2010-10-28 WO claimed
CN-1079738-A Heterobicyclic compounds RECORDATI CHEM PHARM (CH) 1993-12-22 CN claimed
EP-0566288-A1 Flavone derivatives RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1993-10-20 EP claimed
WO-1993017007-A1 HETEROBICYCLIC COMPOUNDS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A. (IT) 1993-09-02 WO claimed
EP-0100250-B1 METHYLFLAVONE DERIVATIVES NIPPON SHINYAKU COMPANY, LIMITED (JP) 1987-03-04 EP claimed
EP-0100250-A2 Methylflavone derivatives NIPPON SHINYAKU COMPANY, LIMITED (JP) 1984-02-08 EP claimed