Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | RET | P07949 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | KDR | P35968 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methyl-2-Phenyl-4H-Chromen-4-One SCHEMBL694139 | 0.90 | ALDH1A1 (0.68) | TSHRLMNATP53RETHTT | |
| SCHEMBL311968 | 0.87 | CYP3A4 (0.72) | TSHRLMNATP53RETHTT | |
| SCHEMBL27406417 | 0.87 | DDR2 (0.58) | TSHRLMNATP53RETHTT | |
| SCHEMBL29839889 | 0.86 | LMNA (0.61) | TSHRLMNATP53RETHTT | |
| SCHEMBL29839875 | 0.86 | LMNA (0.61) | TSHRLMNATP53RETHTT | |
| SCHEMBL10022780 | 0.86 | TNKS (0.57) | TSHRLMNATP53RETHTT | |
| SCHEMBL27404210 | 0.84 | ABCG2 (0.76) | TSHRLMNATP53ALDH1A1KDM4E | |
| SCHEMBL29129514 | 0.84 | TP53 (0.68) | TSHRLMNATP53RETHTT | |
| SCHEMBL10037935 | 0.84 | TP53 (1.00) | TSHRLMNATP53RETHTT | |
| SCHEMBL31316450 | 0.81 | MAPT (0.74) | TSHRLMNATP53RETHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10152486-A | — | — | None | — | — | JP | disclosed |
| JP-H10152486-A | PRODUCTION OF 3-ALKYLFLAVANONOL DERIVATIVE | KAO CORP | 1998-06-09 | — | — | JP | disclosed |